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Hesperidin methyl chalcone

INCI Name : Hesperidin methyl chalcone
Synonyms : 2-Propen-1-one,1-[4-[[6-O-(6-deoxy-alfa-L-mannopyranosyl)-
3-(3-hydroxy-4-methoxyphenyl)-, (E)-
中文名称 : 橙皮苷甲基查尔酮
日文名 :   ヘスペリジンメチルカルコン
한글 이름 :  헤스페리딘메칠찰콘
CAS No. : 24292-52-2
EINESC  : 246-128-2
Molecular Formula : C29H36NO15

Hesperidin methyl chalcone



Appearance :   White powder
Identification :    Meet the requirement
Assay (%) :   90-100.5
Loss on drying (%) :   ≤6.0%
Ignition residue  % :   ≤0.5
Heavy metals :   ≤20 ppm
Aerobic Bacterial :   ≤1000 CFU/g
Molds & Yeast Count  :    ≤100 CFU/g
Fecal Coliforms  :  Negative


1.   Hesperidin Methyl Chalcone is a derivative of the flavonoid hesperidin and is found in citrus fruits like oranges and grapefruit and is often used to reduce dark circles under the eyes
2.   It lowers the filtration rate of capillaries, and less blood flowing though capillaries close to the surface of the skin potentially means less dark bluish discoloration under the eyes
3.   It's also thought to prevent leaking from the veins below the eyes, also preventing the dark blue look from blood leaking below the surface of the skin.
4.   Hesperidin Methyl Chalcone is also thought to support and protect the integrity of the vascular system, specifically the capillaries and veins. It has been shown to help strengthen capillaries by increasing capillary resistance, decreasing capillary permeability, and allowing vessels to dilate more easily
5.   Well abosrbed compared with hesperidin. Safe for use near the eyes.
6.   Product Containing Hesperidin Methyl Chalcone
Mark Lees Pept Eyes, Derma Radiant Ageless Eyes, Provectin Plus Advanced Eye Cream, YBF Correct, MD Skincare Lift Lighten Eye Cream


1.  strengthen capillary walls, reduce capillary permeability, prevent from blood stasis;
2.  reduce dark circles and bags under the eyes;
3.  treat varicose veins
4.  lighten skin by reduce melanin synthesis;
5.  protects skin from UV-caused damage and cell ageing;
6.   restores the barrier function of the skin, improving hydration, regulating pH and promoting skin cell proliferation;
7.  antioxidant, reduce the activity of oxidase, combat the inflammation and cell damage caused by free radicals, reduce various types of pain caused by inflammation.


Hesperidin methyl chalcone can be used in products of:
 ﹒Anti-redness and eye care
﹒ Sun damage protection 
﹒ Capillary health
﹒ Lightening & brightening
﹒ Reduce dark circles under the eyes
﹒ Restore barrier function
﹒ Anti-inflammatory

Use Level :   0.5-3.0%




msds Hesperidin methyl chalcone.pdf








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