INCI Name : Glycyrrhiza glabra (Licorice) root extract
Plant Name : Glycyrrhiza glabra
Common name : Licorice
Synonyms : Glycyrrhiza Extract; Glycyrrhiza Flavonoids; Glycyrrhiza Glabra Extract; Kanzou Ekisu ( JPN);
Kanzou Furabonoido ( JPN); Licorice Flavones-40; Licorice extract
Family : Fabaceae
Part used : Roots
Composition : >40% glabridin; >90% glabridin
CAS No. : 59870-68-7; 84775-66-6; 97676-23-8 C20H22O4 326.40
EINECS : 283-895-2
Structure:
BIOLOGICAL ACTIVITY
1. Tyrosinase Inhibitor: The inhibitory effect on the activity of tyrosinase is stronger than that of Arbutin, Kojic acid,
vitamin C and hydroquinone. It can further inhibit the activity of tyrosinase retative protein ( TRP-2)-dopachrome
tautomerase. It possesses a quick and highly effective whitening function.
2. Scavenger of oxygen free radical: It has SOD-like activity to dispel oxygen free radical
3. Anti-oxidant: It has an approximate resistant force to activated oxygen as Vitamin E.
4. Anti-inflammatory
5. Anti-microbial
APPLICATION
Reduction of melanin synthesis
Skin-tone lightening
Reduction of age-spots
Soothing agent
Prevention of oxidative damage
Anti-microbial
GENERAL INFORMATION:
Glabridin (HPLC) 40% 90%
Appearance Yellow-brown or reddish-brown powder Almost white powder
Solubility Dissolve in 1,3-butylene glycol to get a clear solution
USE LEVEL: Recommendatory volume of usage: 0.05~0.1%
Fig 1. Effect of Glabridin-40 on Melanin content in B16 melanocyte
Fig 2. Effect of Glabridin-40 on Melanin content in human melanocyte
Fig 3. The rapid lightening effect of Glabridin on inhibiting the main enzyme
melanogenesis, such as the activity of tyrosinase, the activity of TRP-2
Blank X200sqm |
Glabridin-40 2ppm |
Glabridin-40 5ppm |
Glabridin-40 10ppm |
Glabridin-90 2ppm |
Glabridin-90 5ppm |
Fig 4. The quantity of melanocyte on the comparative electrical-lens photos on Glabridin-90 and Glabridin-40 to B16 cells
Documentation: