INCI Name | : | Ciclopirox Olamie |
Chemical Name /Synonyms | : | Ciclopirox ethanolamine; 6-Cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one 2-aminoethanol (1:1) |
CAS No. | : | 41621-49-2; 29342-05-0 ( free form) |
EINECS | : | 255-464-9 |
Molecular Formula | : | C12H17NO2.C2H7NO; C14H24N2O3 |
Structure :
Ciclopirox Olamine structure
Function
Cosmetic Biocide
Ciclopirox has broad-spectrum action against dermatophytes, yeast, and fungi. Its anti-inflammatory activity has been demonstrated in human polymorphonuclear cells. This agent also inhibits prostaglandin and leukotriene synthesis. Ciclopirox olamine was effective and safe for mild-to-moderate dandruff.
General Information:
Description | : | White or pale yellow crystalline powder |
Identification | : | IR corresponds to that of reference standard |
Loss on drying (%) | : | Not more than 1.5 |
Residue on ignition (%) | : | Not more than 0.1 |
Heavy metals (ppm) | : | Not more than 10 |
Ethanolamine content | : | 223~230mg/g |
pH | : | 8.0-9.0 |
Related compounds | : | Impurity A<0.5%; Total Impurities<0.5%; Any single impurity<0.1% |
Assay (%) | : | 98.0-101.0 |
Use Level
Recommendatory amount of usage: 1-1.5%
Documentation: